The Charleville Chamber of Commerce says the closure of two major retailers in the town has nothing to do with the town or the drought.
It is holding public meeting with the Murweh Shire Council this Friday morning, to update residents on what is happening to entice new business.
Target and Crazy Clarks are due to close in the community this weekend.
The chamber's John Burey says there are solid opportunities for businesses but it is a difficult time to attract new players to the region.
"The drought affects all of us, so when the rural properties are struggling, they've just got to batten down the hatches and get through this and one of those things is only spending money on the necessities, and at the moment that is to keep their livestock stock alive," he said.
"That's the problem with these two stores closing at the moment, is that it is not the ideal time for someone new to come in and have a look and think this is a vibrant little town."
Mr Burey says the chamber is keen to identify gaps in local commerce and hear ideas to help businesses thrive.
"Corporate businesses seem to be moving out of rural areas and that leaves opportunities for smaller businesses or private companies to move in and fill that gap," he said.
"People have been concerned that the town is dying and there is a problem and what we are trying to reassure people is that it is absolutely nothing to do with Charleville.
"Unfortunately we just happen to have two of those [stores closing] in our town."
© ABC 2014
20:55 EDT A blistering heatwave is scorching western Queensland with temperatures above 40 degrees Celsius and will spread to the south-east later this week.